Antibiotic resistance arising via chromosomal mutations is typically specific to a particular antibiotic or class of antibiotics.We have identified mutations in genes encoding ribosomal components Brake Pads in Mycobacterium smegmatis that confer resistance to several structurally and mechanistically unrelated classes of antibiotics and enhance sur
The goal of this study is twofold.The first one is to assess the applicability of approaches based on dynamicmechanical analysis to investigate the viscoelastic properties of a self-adhesive synthetic rubber.The second goal is to identify the parameters of a viscoelastic model which accurately represents the frequency-dependent mechanical propertie
Abstract Background Effective bone formation relies on osteoblast differentiation, a process subject to intricate post-translational regulation.Ubiquitin-specific proteases (USPs) repress protein degradation mediated by the ubiquitin-proteasome pathway.Several USPs have been documented to regulate osteoblast differentiation, but whether other USPs